Jordan Nof is co-founder and managing partner at Tusk Venture Partners, where he operates with a "regulation follows innovation" thesis that treats inevitable regulatory scrutiny as an investment lens rather than just a risk factor. He has built a dual evaluation process that combines traditional venture analysis with an in-house political affairs team that creates 50-state regulatory roadmaps for portfolio companies, and he encourages founders to engage regulators proactively to help shape industry rules as a competitive advantage.

• Specializes in companies operating within highly regulated markets. This investor explicitly highlights a thesis focused on navigating complex government rules, evident when announcing their third fund dedicated to this sector and when discussing how FDA rulings impact investment decisions in diagnostics.
• Prioritizes digital health innovations that democratize access to care and modernize healthcare infrastructure. There is strong, repeated support for portfolio companies like Alma, which focuses on affordable behavioral health, and Wheel Health, which aims to break down barriers in care delivery.
• Focuses on financial technology infrastructure and tools that support small businesses. This includes predictions that fintech companies building backend systems for small and mid-sized enterprises will grow significantly, alongside backing payment infrastructure startups like Lithic.
• Offers strategic advice on navigating economic volatility and fundraising challenges. Frequently shares insights on how founders should manage talent retention and survive funding slowdowns, suggesting a preference for leadership teams that show resilience during market shifts.
• Engages deeply with the intersection of policy and emerging technology, particularly in crypto and digital assets. This involves participating in discussions about the state of industry regulation and analyzing how geopolitical risks affect the broader crypto market.