Amplify began as a spinout of the MaRS Catalyst Fund and stands out for requiring every portfolio company to complete a B Corp assessment and track a board-level impact metric, while focusing on hard, regulated categories like long-duration energy storage, autonomous machinery, synthetic biology, and cardiac rehab technology from early stages through major scale-ups across Canada, including Quebec. With Fund III, it is growing into a broader North American lead investor for climate, health, and work-focused startups, writing $1–3 million checks backed by a mix of institutions, foundations, and public programs, and arguing that strong impact practices make companies more resilient and better funded.