Lynne Chou O'Keefe brings unusual hands-on medical device experience from Guidant and Abbott Vascular to venture capital, having launched over ten product families before becoming a VC, which gives her a deeper understanding of product development, regulation, and commercialization than most digital health investors. She was an early board member at Livongo during its journey from startup to IPO and multibillion-dollar acquisition, and now focuses exclusively on early-stage digital health companies at Define Ventures, positioning herself as a day-zero partner who helps founders shape business models and navigate the complex intersection of consumer experiences and healthcare reimbursement systems.
About their Fund
Sectors
Health, AI, SaaS, Consumer, Insurtech
Rounds
Seed - Series A
Avg Check Size
$750K - $6M
Notable Investments
Define Ventures runs a free "AI Fellows" program that gives aspiring healthcare AI founders direct access to former Fortune 100 health CEOs and tailored sessions by sub-sector to work through real go-to-market tactics, essentially serving as a practical AI founder school embedded inside a VC firm. The firm has built an enduring "family" community where alumni retain open communication channels with partners for ongoing advice and networking long after the formal program ends, while systematically plugging portfolio companies into a pre-built network of leading payers, providers, employers, and life-science companies to accelerate commercial pilots and distribution.
Other partners at the fund
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Notable Fund
Investments
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