Lynne Chou O'Keefe

Founder and Managing Partner, Define Ventures
Lynne Chou O'Keefe launched 10+ device product families pre-VC, offering deep product expertise as a day‑zero partner to early-stage digital health founders—an early Livongo board member through its multibillion‑dollar exit.
How to contact Lynne Chou O'Keefe
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$750K - $6M
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Does their fund Lead?
No
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Geos their fund invests in
USA
Lynne Chou O'Keefe
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Health
AI
SaaS
Consumer
Insurtech
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$750K - $6M
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No
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About Lynne Chou O'Keefe

Lynne Chou O'Keefe brings unusual hands-on medical device experience from Guidant and Abbott Vascular to venture capital, having launched over ten product families before becoming a VC, which gives her a deeper understanding of product development, regulation, and commercialization than most digital health investors. She was an early board member at Livongo during its journey from startup to IPO and multibillion-dollar acquisition, and now focuses exclusively on early-stage digital health companies at Define Ventures, positioning herself as a day-zero partner who helps founders shape business models and navigate the complex intersection of consumer experiences and healthcare reimbursement systems.

About their Fund

Define Ventures

Sectors
Health, AI, SaaS, Consumer, Insurtech
Rounds
Seed - Series A
Avg Check Size
$750K - $6M

Define Ventures runs a free "AI Fellows" program that gives aspiring healthcare AI founders direct access to former Fortune 100 health CEOs and tailored sessions by sub-sector to work through real go-to-market tactics, essentially serving as a practical AI founder school embedded inside a VC firm. The firm has built an enduring "family" community where alumni retain open communication channels with partners for ongoing advice and networking long after the formal program ends, while systematically plugging portfolio companies into a pre-built network of leading payers, providers, employers, and life-science companies to accelerate commercial pilots and distribution.

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