Mike Nicholls is a Partner at Main Sequence Ventures who positions himself as a talent scout for deep-tech founders, focusing unusually heavily on teaching sales and marketing execution rather than just providing capital, and actively runs sales, marketing and hardware events for portfolio companies. His background includes prior experience as Director of Invention Development at Intellectual Ventures where he commercialized inventions and assembled engineering teams, plus multiple founder and CEO roles, giving him hands-on experience scaling hardware- and IP-heavy startups across semiconductors, AI, renewable energy, and life sciences.
About their Fund
Sectors
Deeptech / Hardware, Food & Ag, Climate, Health, Space
Rounds
Seed - Series B+
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Notable Investments
Main Sequence Ventures is CSIRO's commercialisation engine that systematically builds companies from scratch around publicly funded research rather than just funding existing startups, co-designing ownership structures with research organisations and industry partners. The fund organises around mission-style challenges like feeding 10 billion people and decarbonisation, managing over A$1B across federal programs while serving as Australia's national-scale bridge from lab to market through partnerships with 28+ universities.
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Popular Investors
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Deeptech / Hardware
Robotics
Biotech
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12
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Unknown
Pre-Seed - Seed
Unknown
$400K - $2M
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Defense
Deeptech / Hardware
Energy
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7
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Unknown
Pre-Seed - Series A
Unknown
$100K - $5M
Unknown
Defense
Deeptech / Hardware
Energy
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7
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Unknown
Pre-Seed - Series A
Unknown
$100K - $5M
Unknown
Biotech
Health
Deeptech / Hardware
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2
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Unknown
Pre-Seed - Seed
Unknown
$250K - $2M
Unknown
Climate
Deeptech / Hardware
Materials
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4
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Unknown
Pre-Seed - Seed
Unknown
$400K - $1.5M
Unknown
Deeptech / Hardware
Robotics
Biotech
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7
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Unknown
Pre-Seed - Seed
Unknown
$400K - $2M
Unknown
Deeptech / Hardware
Robotics
Biotech
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2
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Unknown
Pre-Seed - Seed
Unknown
~$750K
Unknown
Fintech
Deeptech / Hardware
Devtools
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2
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Unknown
Pre-Seed - Series A
Unknown
$250K-$1M
Unknown
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