Pietro Puglisi stands out for actively searching out promising science himself, then working closely with scientists from day one to help build companies from the ground up, as he did with IAMA Therapeutics and Kither Biotech, and he later sits on their boards as chairman or director rather than stepping back after investing. He also has a clear approach to risk, saying Claris wants to keep the biological risk in a program but strip away as much of the other risk as possible through clean program design and clear clinical paths.
About their Fund
Claris Ventures is a Turin-based venture fund that invests exclusively in early-stage biotech therapeutics, building companies from the Italian research ecosystem—including academic spinouts and Italian scientists working abroad—by co-founding companies, shaping strategy, and staying involved through the board, with the goal of reaching early clinical proof and pharma partnerships; it has been called the first and main Italian VC focused on biotech, backed by anchor investors EIF and CDP Venture Capital. Its portfolio has attracted deals with Sanofi, Bristol Myers Squibb, and ONO Pharmaceutical, and the fund also works with Evotec to give portfolio companies access to preclinical development and manufacturing, while its Lever Bio initiative sources drug candidates directly from Italian universities and research centers before companies are even formed.
















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