Sean Cheng, PhD

Managing Director, Ascension Ventures
Sean Cheng combines a PhD in medical-device fluid dynamics and FDA CDRH regulatory experience, and manages medtech investing across 13 health systems and 460+ acute-care facilities for clinical testing.
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About Sean Cheng, PhD

Sean Cheng brings an uncommon combination of deep technical training (PhD in engineering focused on medical device fluid dynamics) and hands-on regulatory experience at the U.S. FDA's Center for Devices and Radiological Health, giving him a full-stack view from bench science to regulation rarely found in venture investors. He manages medtech and life sciences investing on behalf of 13 health systems and more than 460 acute care facilities across 25–35 U.S. states, giving him direct access to diverse real-world care settings and the ability to rapidly pressure-test startups with frontline clinical leaders from multiple health systems.

About their Fund

Ascension Ventures

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Health, Medtech, Biotech, Data, Cybersecurity
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Ascension Ventures is the strategic investment arm of 13 leading U.S. health systems across 22 states, representing more than $100 billion in annual operating revenue, which gives it direct access to large provider networks that most VCs don't have. The firm's financial returns flow back to its health system limited partners—many of which are nonprofit health systems—linking venture outcomes to hospital capital needs and community health initiatives rather than to traditional financial LPs.

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