Sizi Chen studied music and management science at Stanford and later worked on creative technology projects at the MIT Media Lab, including a civic music project that used custom apps and crowdsourced city audio, before moving into venture investing at FoundersX. Today she invests across AI chips, energy, and digital health, backing companies in areas as different as 3D chip design, Alzheimer's treatment, patent-law AI, and women's mental health, and she has argued that digital therapeutics should be held to pharma-level clinical standards while having the potential to become some of the most profitable companies in healthcare.