Wes Selke co-founded HUB Ventures, an accelerator for social impact startups, before joining Better Ventures, giving him hands-on experience coaching founders rather than just providing capital. He operates from Oakland and backs technically complex companies like AI-enabled green chemistry platforms, while arguing that mission-driven founders outperform because they attract better talent than large tech companies.

• Strong conviction in the future of food technology, particularly alternative proteins and cellular agriculture. He anticipates a cultural shift where future generations will view eating animal meat as an outdated practice, and he actively highlights investments in fungi-based meats and cultivated fat technologies that offer scalable, healthier solutions.
• Focus on climate technology as a massive, defining market opportunity. He views the current push to decarbonize the economy as being comparable to the early days of the internet boom, wondering if the sector is currently facing a pivotal adoption moment similar to the launch of Netscape or Facebook.
• Dedication to democratizing prosperity and narrowing the wealth gap through venture capital. He expresses a desire to back founders who are building solutions that provide access to high-growth careers, such as those in AI or green energy, and supports tracking diversity metrics to ensure more inclusive funding.
• Interest in deep science and synthetic biology applied to sustainability. He looks for startups leveraging complex innovations, such as using artificial intelligence to discover crop genomes that are resistant to climate change, or exploring the potential of algae and microbial fermentation to create value-added products from excess supply.
• Advocacy for repairing essential social infrastructure like childcare and education. He has highlighted the economic imbalances in the care sector, noting the irony that service jobs often pay better than roles responsible for educating children, and looks for private innovations that can support these public needs.