Yi He co-founded Binance after growing up in rural China with limited economic opportunity, which shaped her focus on using crypto to improve financial access, and she brings an unusually multidisciplinary background including roles as TV anchor, teacher, psychotherapist, and marketing executive to her venture investing at Binance Labs. She is one of the few top-tier crypto venture leaders who is simultaneously a major operator, having helped drive Binance to become the world's largest exchange in six months while managing Binance Labs' multi-billion-dollar assets across 200+ projects, and she actively integrates social impact through spearheading Binance Charity's tens of millions in donations to education and poverty alleviation.

• Valuing resilience and optimism in the face of market skepticism. She frequently emphasizes that while pessimists might sound smart, it is the optimists who actually drive progress, suggesting she prefers founders who can weather criticism and stay focused on building despite fear and uncertainty in the market.
• Prioritizing regulatory compliance and professionalization. There is a recurring theme regarding the importance of hiring professional compliance staff and improving internal programs, indicating that she values startups that take legal structures and cooperation with authorities seriously rather than trying to skirt rules.
• Focusing on long-term infrastructure and historical impact. She views the current work in the crypto space as laying the foundation for future finance, comparing the industry to a snowball that needs a long hill to accumulate value, which implies an interest in projects aiming for generational impact rather than short-term flips.
• Centering community engagement and user appreciation. She actively highlights initiatives that reward content creators and regular users, such as campaigns for the platform's content hub, showing a strong preference for projects that treat their community as a core asset rather than just a customer base.
• Interest in sustainable tokenomics and project health. She pointed out high-quality analysis regarding the lifecycle of projects, specifically noting how milestone-based unlocking of tokens can prevent early collapses, suggesting she looks for founders who design their financial structures to align with long-term delivery.
• A constant search for top-tier talent. She posts repeatedly about hiring, implying that she evaluates the strength of a team and their willingness to learn from competitors and the broader market as a key indicator of success.