Zoe Chambers is a Partner on Frontline's Seed fund who focuses on climatetech, AI and healthtech investments, with 50% of her career investments going to female-led businesses as part of her mission to back overlooked entrepreneurs. She built her venture perspective on top of a background as a corporate lawyer at Jones Day and investment banker at Goldman Sachs, and previously led the deeptech investment team at Octopus Ventures where she backed technically intensive and climate-oriented companies.
What they've been talking about across their social media accounts

- Extensive focus on US expansion strategy for European founders, specifically offering tactical advice on checking readiness levels, selecting NYC as a landing spot, and understanding the nuances of transplanting company culture across the Atlantic.
- Deep interest in B2B SaaS operational mechanics, frequently sharing specific insights on sales team structure, such as using generalist sellers for multi-product strategies and ensuring customer success teams focus on retention rather than just sales.
- Enthusiasm for the transformative potential of AI, particularly regarding foundation models and how artificial intelligence might upend traditional service businesses or provide decision augmentation for large enterprises like Deloitte and Meta.
- Support for the modern, distributed workforce, highlighting investments in companies that simplify global employee benefits and reduce the friction of managing international teams.
- Commitment to diversity in the startup ecosystem, often engaging with communities of female founders and celebrating successful women in the venture space.
About their Fund
Sectors
SaaS, Enterprise, Fintech, AI, Data
Rounds
Pre-Seed - Series B+
Avg Check Size
$100K - $10M
Notable Investments
Frontline operates two specialized funds that form a "two-way transatlantic bridge": Frontline Seed backs European B2B software founders expanding into the U.S., while Frontline Growth backs later-stage U.S. B2B companies (Series B-D) entering Europe, positioning them as cross-Atlantic expansion specialists rather than generalist VCs. The firm functions more like a "go-to-market consultancy plus VC," producing detailed operational playbooks and data-driven research (including a 100-page "US Playbook") based on analysis of hundreds of B2B software companies, which founders and media outlets use as reference manuals for transatlantic expansion.
Notable Fund
Investments
Sheets they're in
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Sheets they're Fund is in
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Popular Investors
investor name
Active in
Rounds
Avg. Check
Links
Deeptech / Hardware
Robotics
Biotech
+
12
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Unknown
Pre-Seed - Seed
Unknown
$400K - $2M
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Defense
Deeptech / Hardware
Energy
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7
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Unknown
Pre-Seed - Series A
Unknown
$100K - $5M
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Defense
Deeptech / Hardware
Energy
+
7
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Unknown
Pre-Seed - Series A
Unknown
$100K - $5M
Unknown
Biotech
Health
Deeptech / Hardware
+
2
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Unknown
Pre-Seed - Seed
Unknown
$250K - $2M
Unknown
Climate
Deeptech / Hardware
Materials
+
4
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Unknown
Pre-Seed - Seed
Unknown
$400K - $1.5M
Unknown
Deeptech / Hardware
Robotics
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+
7
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Unknown
Pre-Seed - Seed
Unknown
$400K - $2M
Unknown
Deeptech / Hardware
Robotics
Biotech
+
2
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Unknown
Pre-Seed - Seed
Unknown
~$750K
Unknown
Fintech
Deeptech / Hardware
Devtools
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2
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Unknown
Pre-Seed - Series A
Unknown
$250K-$1M
Unknown
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