Brittany Walker is a venture capital investor at CRV who describes herself as a "first check investor in technical founders," backing deeply technical teams solving hard problems in AI, infrastructure software, and frontier technology from pre-seed through Series A, drawing on her background as a former federal government contractor and Uber operator-analyst rather than traditional finance. She co-founded "The Table," a community for women in enterprise, and helped create "Interchange," the first free job board solely focused on LA startups, while maintaining recognition at CRV for her tenacity in uncovering investment opportunities in the data and AI space.

• Deep focus on the multimodal data stack and the infrastructure required to support modern AI. Frequently highlights investments in companies like LanceDB and Daft that are redefining how data is processed and stored, while pointing to Palantir as a successful example of combining a robust data layer with a flexible application layer.
• Conceptual interest in the evolution of AI agents and how they change user interaction. Frames agent-assisted applications as expertise as software and suggests that terminals are evolving into new AI companions, signaling an appetite for startups rethinking the interface between humans and autonomous systems.
• Attention to the shifting landscape of developer tools and the transition from developer experience to agent experience or AX. Discusses the importance of first defaults for developer-led companies and critiques major labs like Anthropic when they prioritize lock-in over product improvement, advocating instead for open standards.
• Support for the intersection of life sciences and artificial intelligence. Identifies life sciences as one of the most meaningful frontiers for AI acceleration, specifically citing companies working on clinical trial outcomes as examples of high-impact deep tech that justifies significant venture capital support.
• Emphasis on founder-led sales and commercial execution. holds the view that the founder must be the primary salesperson initially, noting that if the person who built the product cannot sell it, it is unlikely anyone else will be able to succeed.