David Sze built his venture capital approach from years as a product operator at companies like Electronic Arts and Excite, where he managed hundreds of people through hypergrowth, giving him firsthand experience that most finance-background investors lack. He deliberately seeks out controversial investment opportunities that other partners might reject, leading Greylock's early bets on Facebook, LinkedIn, and Discord by focusing on founder quality and network effects rather than consensus deals.

• Deep pride in family achievements within the arts and sciences. Frequently shares enthusiastic updates about his sister Sarah Sze and her major art installations at venues like the Guggenheim and Storm King Art Center, as well as celebrating the literary and medical work of his brother-in-law Dr. Sid Mukherjee, specifically regarding his book The Song of the Cell.
• Active promotion of portfolio companies and their community impact. Consistently amplifies news related to Nextdoor, such as their transparency reports and insights on consumer behavior, while also highlighting major press features for other investments like Roblox.
• Enthusiasm for artificial intelligence and new venture partnerships. Expressed significant excitement about collaborating with Mustafa Suleyman and Reid Hoffman on Inflection AI, signaling a strong interest in the next generation of consumer technology.
• Support for firm colleagues and the wider industry network. Regularly congratulates partners like Saam Motamedi on professional recognition and welcomes new team members such as Jacob Andreou, showing a focus on talent density within his own firm.
• Advocacy for science and innovation at a policy level. Encourages political action to protect government funding for science, viewing innovation as a critical component of national success and quality of life.