Vast Ventures is one of the few manifesto-driven venture capital funds that organizes around five concrete objectives including improving worldwide health and happiness and promoting resource sustainability, using these pillars as the primary lens for investment selection rather than a traditional sector or stage thesis. The fund positions itself as both investor and company-builder, emphasizing that they have "started and grown" companies beyond just funding them, with a portfolio concentrated in enabling infrastructure and platform companies like Ginkgo Bioworks and ASAPP that align with their goal of increasing human potential and productivity.