John Maraganore built his career as a scientist first, inventing the drug bivalirudin and then leading Alnylam Pharmaceuticals as it turned RNA interference from an early research idea into real approved medicines, and he still favors backing platform companies over single drug bets, as shown by his role as co-founder and Executive Chair of City Therapeutics. He's also known for mentoring young biotech entrepreneurs, highlighted by Alnylam's Nucleate partnership creating an award in his name for science entrepreneurship.