Sarah Hymowitz, PhD

Partner, The Column Group
Sarah Hymowitz combines a UCSF PhD in biophysics with 22 years at Genentech—including VP of Protein Sciences—oversight of 35+ large-molecule clinical candidates and a leading role in discovering Venclexta.
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About Sarah Hymowitz, PhD

Sarah Hymowitz is a venture capital investor at The Column Group who spent 22 years at Genentech rising to Vice President of Protein Sciences, where she oversaw the development of more than 35 large-molecule clinical candidates and played a leading role in discovering Venclexta, a first-in-class cancer drug. Her unusually deep hands-on drug discovery experience, combined with her PhD in Biophysics from UCSF, gives her a rare scientific background among venture investors focused on biotech company formation.

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The Column Group

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Biotech, Health
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The Column Group operates as a venture ecosystem rather than a traditional VC fund, systematically creating single-drug biotech companies through its affiliated TCG Labs-Soleil engine instead of primarily backing existing startups. The fund has achieved documented outlier performance with a ~397% IRR on certain early-stage drug-discovery investments, distinguishing itself through deep scientific platform bets led by research-heavy leadership from the translational science community.

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