Damian Crowther trained as a neurologist and ran a Cambridge dementia research lab before spending six years in AstraZeneca Neuroscience, then moved into venture as an Entrepreneur in Residence at Oxford Science Enterprises, Cambridge Innovation Capital, and the Dementia Discovery Fund, all while co-founding companies like GPnotebook, EndLyz for Parkinson's, and TRIMTECH Therapeutics, which raised $31 million in seed funding to selectively break down toxic protein aggregates. His work centers specifically on protein aggregation and how it can be used to treat neurodegeneration and inflammation, and he describes himself simply as a neuroscience entrepreneur rather than a traditional investor.
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Biotech, Health, Medtech, Under-represented founders
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Dementia Discovery Fund (DDF) was set up as a collaboration between charities, pharmaceutical companies, and the UK government rather than a typical venture fund, and it focuses on parts of dementia biology beyond the usual amyloid-beta approach, often building new companies itself when promising science exists but no company does yet—already accounting for half its portfolio. It also runs its own drug-discovery infrastructure, including a 500,000-molecule compound library through DDF ChemCo, and draws on an unusually wide investor base, from Bill Gates and the NFL Players Association to AARP and the UK government, while staying exclusively focused on dementia therapeutics.
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