John Orloff

Venture Partner, Agent Capital
John Orloff is a physician and former R&D leader who scaled pipelines from 3 to 30 programs and now applies AI-based discovery expertise to guide clinical development.
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Nordic and Baltic countries, occasionally outside this geography
John Orloff
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Biotech
Health
Medtech
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About John Orloff

John Orloff joined Agent Capital as a physician and former R&D leader at companies like Novartis, Baxalta, and Alexion, where he helped grow the pipeline from 3 programs to 30, rather than as a traditional financial investor. He now serves on the boards of Zenas BioPharma and BenevolentAI, applying his drug development experience to help guide science-driven companies, including how AI-based discovery can connect to real clinical development.

About their Fund

Agent Capital

Sectors
Biotech, Health, Medtech
Rounds
Seed - Series B+
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Agent Capital was founded by Geeta Vemuri, who previously ran Baxter Ventures and Baxalta Ventures with more than $300 million under management, making her one of only four women in biopharma to have founded a venture capital group and what she described as a rare opportunity for a woman, and specifically a woman of color, in life sciences VC. The firm's team includes former senior operators from companies like Alexion, Baxalta, Baxter, Novartis, J&J, Cephalon, Ophthotech, MedImmune, and Ipsen, and its first fund, sized at $63.5 million, invested in 15 core biopharma companies focused on rare disease, oncology, neurology, and immunology, with four of those companies going public.

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