Samantha Lewis

Partner, Mercury
Since 2017 Samantha Lewis has studied blockchain, founded companies in agribusiness, logistics and deep tech, focuses on blockchain for established businesses, teaches VC at Rice and champions women in VC.
How to contact Samantha Lewis
Stages their fund invests in
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Sectors their fund invests in
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Avg Check
$1M–$5M; Pre-Seed $100K
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Does their fund Lead?
No
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Geos their fund invests in
Samantha Lewis
Stages their fund invests in
N/A
Sectors their fund invests in
SaaS
AI
Fintech
Data
Enterprise
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Avg Check
$1M–$5M; Pre-Seed $100K
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Leads?
No
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About Samantha Lewis

Samantha Lewis has studied blockchain since 2017 and focuses on startups that use it to solve real problems for established businesses, backed by her own experience founding companies in agribusiness, logistics, beauty, and deep tech, plus her move from Houston to Austin to strengthen ties across the Texas Triangle. She also teaches venture capital at Rice University, invests in financial infrastructure companies like Plasma, Profitr, OpenTrade, and LISNR, hosts conversations on topics like stablecoins, and advocates for more women holding investment decision-making power in venture capital.

About their Fund

Sectors
SaaS, AI, Fintech, Data, Enterprise
Rounds
Pre-Seed - Series A
Avg Check Size
$1M–$5M; Pre-Seed $100K

Mercury is a venture fund that focuses specifically on SaaS and data-platform founders in smaller tech markets outside Silicon Valley and other coastal hubs, betting that founders who understand local industries will lead the next wave of vertical AI companies. It backs this focus with structured support such as the Mercury Method, OpsHygiene, an in-house AI lab called Quicksilver Labs, and liquidity planning that starts 18-24 months before a company is ready for M&A, while also investing in overlooked real-economy sectors like energy, industrials, healthcare, construction, manufacturing, and defense.

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